Hydrochlorothiazide is a thiazide diuretic that helps prevent your body from absorbing too much salt, which can cause fluid retention. Losartan keeps blood vessels from narrowing, which lowers blood pressure improves blood flow. The combination of hydrochlorothiazide (12.5mg) and losartan (50mg) is used to treat high blood pressure  and to reduce the risk of stroke in people with hypertension.
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Generic Name | Losartan |
Popular Brands | Acuretic, Aldactazide, Aldoril, Apresazide, Aquarills, Aquarius, Bremil, Caplaril, Capozide, Chlorosulthiadil, Chlorothiazide, Chlorzide, Cidrex, Dichlorosal, Dichlorotride, Dichlotiazid, Dichlotride, Diclotride, Dicyclotride, Dihydrochlorothiazid |
Package | 100ct |
Max Order Size | 5 units |
Package Description | Blister Pack |
Strengths | 50mg-12.5mg |
Hydrochlorothiazide and losartan is a combination medicine used to treat high blood pressure, or to lower the risk of stroke in certain people with heart disease.
Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant.
You should not use this medication if you are unable to urinate, or if you are allergic to penicillin or sulfa drugs.
If you have diabetes or kidney disease, you may not be able to take hydrochlorothiazide and losartan if you are taking medication that contains aliskiren. Tell your doctor about all medicines you use.
In rare cases, hydrochlorothiazide and losartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Losartan is an angiotensin II receptor antagonist. Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Hydrochlorothiazide and losartan is a combination medicine used to treat high blood pressure (hypertension). It is also used to lower the risk of stroke in certain people with heart disease.
Hydrochlorothiazide and losartan may also be used for purposes not listed in this medication guide.
You should not use this medication if you are allergic to hydrochlorothiazide or losartan, if you are unable to urinate.
If you have diabetes or kidney disease, you may not be able to take this medicine if you are also taking a blood pressure medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, or Valturna).
To make sure hydrochlorothiazide and losartan is safe for you, tell your doctor if you have:
FDA pregnancy category D. Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Hydrochlorothiazide and losartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control.
It is not known whether hydrochlorothiazide and losartan passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take this medication with a full glass (8 ounces) of water.
Your blood pressure will need to be checked often. Your kidney function may also need to be checked.
You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual.
If you need surgery, tell the surgeon ahead of time that you are using hydrochlorothiazide and losartan. You may need to stop using the medicine for a short time.
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can further lower your blood pressure and may increase certain side effects of hydrochlorothiazide and losartan.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and losartan, unless your doctor has told you to.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, hydrochlorothiazide and losartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with hydrochlorothiazide and losartan, especially:
This list is not complete. Other drugs may interact with hydrochlorothiazide and losartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Your pharmacist can provide more information about hydrochlorothiazide and losartan.